Our new Crystal clear+ tissue clearing system is the only technique that delipidates samples without improve in morphology and with minimal influence on structural integrity.
Megatome is often a vibrating microtome built to portion a broad selection of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With large blade vibrating frequency and minimized blade deflection, Megatome allows substantial-throughput tissue sectioning with uniform area profile, and minimal tissue injury and data reduction.
Antibodies could get weeks to diffuse by way of just a few millimeters of tissue, by using a steep labeling gradient from floor to Main.
Megatome is created for precision: the blade vibrates at a better frequency and larger amplitude assortment than other microtomes, and incorporates a special deflection Handle mechanism.
SE employs a rotational electrical discipline to disperse extremely electromobile molecules (like antibodies or surfactant micelles) throughout a porous sample without harming electrically billed constructions inside the tissue. This enables two-four day clearing of intact organs,
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Megatome can be a novel microtome that allows for top-precision sectioning of an array of tissue samples – from organoids, to arrays of animal organs, to intact human Mind hemispheres – with small tissue harm and knowledge reduction.
eFLASH is a swift tissue labeling method which allows for uniform complete-organ staining in 20 rounds of labeling.
The SmartSPIM gentle sheet microscope presents unparalleled resolution and acquisition pace throughout intact tissue volumes, even though its modular style means that you can improve and customise person factors.
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Leverage the Distinct+ tissue clearing approach, in conjunction with eFLASH and patented stochastic electrotransport systems, to rapidly very clear and label complete organs. Critical highlights and options consist of:
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